The main objective of this project is to agree on one (cycle ergometry only) or two (cycle ergometry and treadmill) cardiopulmonary exercise testing protocols and respective outcome measures which allow(s) assessment of children, adolescents, adults and elderly people with different respiratory diseases and various degrees of pulmonary impairment.
The purpose of this task force is to revise the current literature on OSA with special reference to sleepiness and fitness to drive, in order to provide practical indications on the new EU directive on issuing driving licences in Europe.
Recent papers reviewed the current knowledge in the field of sleep and stroke and made recommendations for their management.
Interpreting pulmonary function test (PFT) requires accurate reference ranges to help distinguish between health and disease and assess the severity and nature of any functional impairment.
Asthma is still characterized by preventable morbidity and mortality, which is enhanced by poor adherence to international asthma guidelines. This task force will have two axons:
The ERS regards the production of a statement on harmonized standards for centres of care and cancer registration in thoracic oncology in Europe as essential for future quality improvement projects.
This Task Force aims to develop a clinical practice guideline based upon a high-level systematic review on various aspects of quality in thoracic oncology care. This document intends to complete the previous narrative literature search developed by the ERS that showed little high-level evidence in this field of interest. The representation of all relevant professions/disciplines in the thoracic oncology care trajectory as well as active patient involvement are fundamental elements of the project concept.
Previously considered as a rare tumor, malignant pleural mesothelioma (MPM) has become a very important public health issue. MPM is a tumor with a poor survival and its diagnosis may be difficult because of differential diagnosis such as pleural benign disease induced by asbestos exposure or pleural metastasis of adenocarcinoma. Management of patients with MPM also remains complicated because they are often referred for evaluation late in the evolution of the disease. The aim of this Task Force is therefore to provide clinicians with new concise, up-to-dated clinical practice guidelines on management of MPM.
In 2005 the ATS/ERS task force on standardisation of lung function testing published the document: Standardisation of the single-breath determination of carbon monoxide uptake in the lung.
This ERS task force will aim to produce European guidelines and standards of care for the diagnosis, investigation, management and follow-up of adult non-CFBE
PCD is a rare inherited disorder of ciliary function resulting in impaired mucociliary clearance. Symptoms include progressive supportive pulmonary disease, chronic rhino-sinusitis, hearing problems and infertility.
Functional evaluation of airway and lung function is still dominated by traditional tests like spirometry, single or multiple breath wash-in/washout and lung diffusion. During the last years, however, a large amount of evidence has been produced regarding the use of alternative approaches for a more complete understanding of lung and airways function in health and diseases.
Hospital Acquired Pneumonia (HAP) and Ventilator Associated Pneumonia (VAP) are the second intrahospital infection carrying a very high morbidity, mortality, and sanitary costs. In the last 5 years a lot of information has been released in the literature as regards ethiopathogenesis, etiology, diagnosis, treatment and prevention of these entities. This new information could motivate changes in clinical practice.
Exercise intolerance is one, if not the most, of the deleterious consequences of pulmonary diseases that has a great impact on patients’ quality of life. Moreover, exercise tolerance is independently related to mayor outcomes such as survival, rate of hospital admissions and overall cost of pulmonary diseases such as COPD. Thus, because exercise tolerance is an important outcome and its assessment, while complex, will result in a better management of patients. Moreover, measuring exercise tolerance is becoming a very relevant issue for both medical practice and in clinical trials.
The purpose of the European Union Standards for Tuberculosis Care (ESTC) is to describe a widely accepted level of care that all practitioners, public and private, should seek to achieve in managing patients who have, or are suspected of having, tuberculosis (TB). The Standards are intended to facilitate the effective engagement of all care providers in delivering high quality care for patients which is essential to restore the health of individuals with TB, to prevent the disease in their families and others with whom they come into contact, and to protect the health of communities.
Acute viral bronchiolitis is a major cause of clinical morbidity. The comparability and interpretation of evidence from clinical studies has been limited by shortcomings in two key areas of study design: disease definition and outcome measurement.
Malignant pleural effusions (MPE) are common, affecting more than 400,000 people in Europe each year. They are associated with a poor prognosis as their presence usually signifies advanced or metastatic disease.
Bronchopulmonary dysplasia (BPD) isachroniclungdisease thatmostcommonly occurs after preterm birth.Theincidence ofBPD hasnot declined over the pastdecade butthe severity and the clinical course of BPD have·changed with current advanced neonatal practice, leading to a new form of BPD.
The contribution of occupational exposure to most respiratory conditions goes unrecognized. Few lung conditions are pathognomonic for work-related disease: pneumoconiosis is the exception rather than the rule.
Protracted Bacterial Bronchitis (PBB) is a paediatric disease and the major cause of chronic wet cough in preschool-aged children.
The assessment of pulmonary exercise hemodynamics provides important clinical information in patients with respiratory and cardiac diseases. Alterations may represent early forms of pulmonary vascular diseases or latent pulmonary and cardiac dysfunction. An increasing number of studies dealing with pulmonary exercise hemodynamics have been performed in recent years.
The number of individuals that use electronic cigarettes (EC) is quickly increasing. In contrast, only very limited data on the potential harmful effects of ECs' or on their potential usefulness for smoking cessation or harm reduction are available. It is the aim of this TF to collect the results from research on various health-related aspects of EC, to identify gaps in our knowledge of EC, and to make recommendations for filling these gaps.
The workshop objectives are to ensure that upon conclusion, participants will be able to explain health effects by solid fuel smoke exposure in developed and developing countries; identify components of solid fuel smoke and biomarkers of smoke exposure; understand mechanisms related to cardiopulmonary diseases due to solid fuel smoke exposure; and describe useful intervention strategies for developed and developing countries.
Clinicians have struggled to apply the 2011 ATS/ERS/JRS/ALAT guideline for the diagnosis and management of idiopathic pulmonary fibrosis (IPF). In up to 50% of IPF patients, the diagnosis of IPF cannot be made without a surgical biopsy. However, it now appears that treatments used for alternative diagnosis may be actively damaging in IPF.
This Task Force includes members of both the ERS and ESRS and thereby combines expertise from across the discipline of sleep medicine and specifically, disordered breathing. It includes two members who are technicians qualified in scoring sleep, both of whom represent their field at national and international levels.
This Task force will establish an European network of clinical experts in HMV to analyse through a survey the current status of services for ventilator-dependent patients and provide a document on appropriate standard procedures, equipment and facilities.
Breath chemical tests consist of wide variety of measurements from the FDA approved exhaled nitric oxide (FENO) measurement to volatile organic compound determination and non-volatile biomarker profiling in the cooled breath sample called exhaled breath condensate (EBC).
The complexity of sleep related breathing disorders has been realized more and more clearly in recent years. Patients present with relevant comorbidities to sleep physicians, especially heart failure, atrial fibrillation, arterial hypertension, stroke. We see developments in medical practice, including the increasing use of opioids for chronic pain, and realize epidemiologic changes, such as the increasing population of obese persons.
The objective of the task force is to produce an updated evidence-based clinical guideline on sarcoidosis focused on treatment, as no guideline was made available since 1999. A very important point will be (a) strict methodology in formulating questions and sub-questions, reporting evidence-based data drawn around sub-questions from the literature and apply a GRADING approach, (b) tight interactions within the TF group using an interactive method and (c) tight implication of patient representatives.
Respiratory muscle function is a major clinical concern not only for respiratory diseases but also for neuromuscular disorders, intensive care or sports medicine for instance. Respiratory muscle testing is therefore of critical importance for patient diagnosis, follow-up and for evaluating the effect of various interventions aiming to improve the respiratory function.
Patients with acute respiratory failure usually require chest imaging technique for diagnosis of the disease, assessment of the progression and for evaluation of the efficacy of the treatment.
Due to the severity of the disease, patients with pulmonary hypertension are in need of a thoroughly monitored rehabilitation program which is supervised by pulmonary hypertension experts.
Interventional bronchoscopy includes associated techniques such as bronchoalveolar lavage, endobronchial and transbronchial biopsies, laser, tracheostomy, endoscopic intubationclosure of bronchopleural fistula, foreign body extraction, bronchial stent placement, drug application, and endobronchial ultrasound.
Although Alpha-1-Antitrypsin Deficiency (AATD) is recognised as a genetic predisposition to emphysema it has been over 10 years since the writing of the last Guidelines. Since then a large descriptive literature and a small number of therapeutic clinical trials have been undertaken. The project of this Task Force is to bring together European expertise in the diagnosis, interpretation of results, patient assessment and management of the disease. This will provide state of the art information for healthcare workers and patients.
Pulmonary diffusing capacity for nitric oxide (DLNO) is a test to measure alveolar capillary membrane conductance. It was developed in the early 1980's by and postulated that by inhaling a small quantity of nitric (NO) and carbon monoxide (CO) together when preforming a diffusing capacity manoeuvre, all the components of diffusing capacity can be obtained simultaneously. Since then, the measurement of DLNO has been made in several studies. As it is nearly 30 years since the inception of DLNO, there are a lot of methodological issues concerning its measurement. It is the objective, therefore, to create a task force that will define the measurement of DLNO throughout the world.
This Task Force intends to develop a document guiding the treatment of TB in settings where mycobacterial cultures, drug susceptibility testing, radiographic facilities, a2nd second-line drugs are routinely available
This Task Force aims to update the document “The forced oscillation technique in clinical practice: methodology recommendations and future developments” published in 2003 in ERJ which summarised the technology at that time, recommended hardware specifications, summarised the clinical data for FOT to inform clinicians and suggested useful areas of need in clinical research.
This Task Force proposal is based on an ERS Research Seminar entitled “Optimizing disease models for lung diseases and drug development”. The concluding remarks of the seminar were that "animal models are critical to understand mechanisms and pathogenesis of pulmonary health and disease, and are indispensable for drug development".
Nontuberculous mycobacteria (NTM) represent over 160 species which vary greatly in their prevalence, pathogenicity, in vitro drug resistance, and response to therapy. Recent studies have documented high and increasing annual prevalences of pulmonary NTM infections in several regions of the world.
The connective tissue disorders (CTDs), also called collagen vascular diseases (CVDs), represent a group of immunologically-mediated inflammatory disorders with highly heterogeneous patterns of organ involvement.
There is currently no consensus for the diagnosis and management of obstructive sleep apnea (OSA) in childhood. Pediatric OSA differs in many aspects from the disease faced in adults.