Standarization of the single-breath determination of nitric oxide uptake in the lung

Chairs: Anh-Tuan Dinh-Xuan & Gerald Zavorsky

Pulmonary diffusing capacity for nitric oxide (DLNO) is a test to measure alveolar capillary membrane conductance. It was developed in the early 1980's by and postulated that by inhaling a small quantity of nitric (NO) and carbon monoxide (CO) together when preforming a diffusing capacity manoeuvre, all the components of diffusing capacity can be obtained simultaneously. Since then, the measurement of DLNO has been made in several studies. As it is nearly 30 years since the inception of DLNO, there are a lot of methodological issues concerning its measurement. It is the objective, therefore, to create a task force that will define the measurement of DLNO throughout the world.